ОРҚА МИЯНИНГ ИНТРАМЕДУЛЛЯР ЎСМАЛАРИ РЕЗЕКЦИЯСИ ҲАЖМИНИ ЧЕКЛАШНИНГ НЕЙРОФИЗИОЛОГИК МЕЗОНЛАРИ
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орқа миянинг интрамедулляр ўсмалари, интраоперацион нейрофизиологик мониторинг, мотор чақирилган потенциаллар (MEP), соматосенсор чақирилган потенциаллар (SSEP), D-тўлқин, резекция ҳажми, нейропротекция, операциядан кейинги неврологик дефицит##article.abstract##
Орқа миянинг интрамедулляр ўсмаларини жарроҳлик йўли билан даволашда мультимодал интраоперацион нейрофизиологик мониторингни қўллашга бағишланган адабиётларнинг тизимлаштирилган шарҳи ўтказилди. Мотор чақирилган потенциаллар (MEP), соматосенсор чақирилган потенциаллар (SSEP) ва D-тўлқин динамикаси, шунингдек, уларнинг операциядан кейинги неврологик дефицит ривожланиш хавфи билан боғлиқлиги таҳлил қилинди. D-тўлқин амплитудасининг дастлабки даражага нисбатан 50% дан ортиқ барқарор пасайиши, айниқса, MEP ва/ёки SSEP сигналларининг йўқолиши билан бирга кузатилганда, барқарор неврологик дефицит хавфининг муҳим прогностик белгиси эканлиги аниқланди. Жарроҳлик манипуляцияларини вақтинча тўхтатиш ва нейрофизиологик сигналларни қайта баҳолашни назарда тутувчи «stop-and-go» концепциясини қўллаш резекция ҳажмини индивидуал белгилаш ва ўсмани максимал даражада хавфсиз олиб ташлаш тамойилини амалга ошириш имконини беради.
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