EPILEPSIYANING TURLI ŞAKLLARI BILAN OĞRIGAN BEMORLARDA MIYA NEYROTROFIK OMILI BDNF VA KORTIZOL DARAJALARINING ÖZIGA XOS XUSUSIYATLARI
##article.subject##:
epilepsiya, fokal epilepsiya, generalizatsiyalaşgan epilepsiya, BDNF, kortizol, neyroplastiklik, neyroendokrin regulyatsiya##article.abstract##
Epilepsiya neyroplastiklikning buzilişi va gipotalamo-gipofizar-buyrak usti bezi (GGB) tizimi faoliyatining izdan çiqişi bilan keçadi. BDNF va kortizol kasallikning oğirlik darajasi hamda şaklining potensial biomarkerlari sifatida e’tirof etiladi, biroq epilepsiyaning turli şakllarida ularning özaro nisbati haqidagi ma’lumotlar bir-biriga ziddir.
Библиографические ссылки
Binder D.K., Scharfman H.E. Brain-derived neurotrophic factor // Growth Factors. 2004. Vol. 22. P. 123–131.
Binder D.K., Croll S.D., Gall C.M., Scharfman H.E. BDNF and epilepsy: Too much of a good thing? // Trends in Neurosciences. 2001. Vol. 24. P. 47–53.
Scharfman H.E. Brain-derived neurotrophic factor and epilepsy // Progress in Brain Research. 2004. Vol. 146. P. 93–100.
Murray K.D., Isackson P.J., Eskin T.A., et al. Altered expression of brain-derived neurotrophic factor and TrkB receptors in epileptic hippocampus // Journal of Neuroscience. 2000. Vol. 20. P. 7570–7579.
Simonato M., Tongiorgi E., Kokaia M. Angels and demons: Neurotrophic factors and epilepsy // Trends in Pharmacological Sciences. 2006. Vol. 27. P. 631–638.
Kanner A.M. Psychiatric and cognitive comorbidities in epilepsy: Current concepts and future directions // Epilepsy & Behavior. 2021. Vol. 121. Article 108052.
Mula M. Cognitive dysfunction in epilepsy: A contemporary review // Epilepsy & Behavior. 2021. Vol. 121. Article 108045.
