PARKINSONIZMNING TARKIBIY VA KLINIK HUDUDIY XUSUSIYATLARI, DIFFERENSIAL YONDASHUV CHORA TADBIRLARI (Qashqadaryo viloyati misolida)
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parkinsonizm, Parkinson kasalligi, differensial diagnostika, Qashqadaryo viloyati, hududiy epidemiologiya, ekzogen omillar, neyrodegeneratsiya, pestitsidlar##article.abstract##
Ushbu maqola Qashqadaryo viloyatida parkinsonizmning epidemiologik ko'rsatkichlari, klinik ko'rinishlari va hududiy xususiyatlarini o'rganishga bag'ishlangan davom etayotgan tadqiqotning dastlabki kontseptual asoslarini va kutilayotgan natijalarini bayon etadi. Tadqiqot 2024–2026-yillar davomida viloyat neyrologiya bo'limlarida kuzatuvdagi 250 nafar bemor materiali asosida olib borilishi rejalashtirilmoqda. Tadqiqotda Parkinson kasalligi, ikkilamchi va atipik parkinsonizm shakllarini differensial tashxislashga zamonaviy yondashuvni ishlab chiqish, shuningdek viloyat sharoitida uchraydigan ekzogen omillar (gerbetsid-pestitsidlar, og'ir metal tuzlari, sanoatlashgan ekologiya, oziqlanish sifati) bilan parkinsonizm rivojlanishi o'rtasidagi bog'liqlikni o'rganish ko'zda tutilgan. Dastlabki taxminlarga ko'ra, etiologik tuzilmada idiopatik Parkinson kasalligi ustunlik qilishi, ikkilamchi va atipik shakllar esa jahon o'rtacha ko'rsatkichiga nisbatan yuqoriroq ulushni tashkil etishi kutilmoqda. Qishloq xo'jalik zonalarida toksik va ikkilamchi parkinsonizm shakllarining nisbati statistik jihatdan muhim darajada farq qilishi va bemorlarda kasallikning klinik kechishiga sezilarni tasir qilishi kutilmoqda. Tadqiqot natijalari asosida hududiy differensial davolash chora tadbirlari ishlab chiqish maqsad qilinmoqda.
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