MOYAMOYA KASALLIGI: adabiyot tahlili
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moyamoya kasalligi, arteriopatiya, miya angiografiyasi, revaskulyarizatsiya, takroriy insult, giperperfuzion sindrom##article.abstract##
Moyamoya kasalligi (MMК) - yirik intrakranial arteriyalarning uzoq muddatli va progressiv okklyuziyasi bilan tavsiflangan kam uchraydigan serebrovaskulyar kasallik. U asosan Sharqiy Osiyo aholisida uchraydi. MMK holatlarining aksariyati sporadik, ammo oilaviy holatlarning kichik foizi mavjud. Irsiylanish usuli autosom dominant bo'lib, to'liq penetratsiyaga ega emas. Tadqiqotlar shuni ko'rsatadiki, MMK uchun sezuvchanlik geni 17-xromosomada joylashgan. Klinik ko'rinish turlicha bo'lib, bemorning yoshi va geografik mintaqasiga bog'liq. Bolalar asosan ishemiya bilan bog'liq nevrologik epizodlarni boshdan kechirishadi, kattalarda esa MMK ham ishemik hodisa, ham intrakranial qon ketish (IQK) sifatida namoyon bo'lishi mumkin. Tashxis qo'yishning oltin standarti miya angiografiyasi bo'lib, u bosh suyagining tagida arteriyalarning "tutunli" ko'rinishini ochib beradi va bu kasallik nomini beradi. Davolash asosan jarrohlik bo'lib, ishemik va gemorragik insultning takrorlanishining oldini olish uchun bevosita va bilvosita revaskulyarizatsiya jarayonlarini o'z ichiga oladi. Biroq, uzoq muddatli yaxshi natijalarni ko'rsatadigan tadqiqotlar tufayli kombinatsiyalangan revaskulyarizatsiya muolajalari endi yuqori aktualik ko’rsatib etmoqda.
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