COMPARATIVE ANALYSIS OF THE RESULTS OF SURGICAL TREATMENT OF PRIMARY AND RELAPSES OF GLIOBLASTOMAS
Keywords:
Glioblastoma, relapse of brain tumor, surgical treatmentAbstract
Glioblastoma multiforme is a malignant tumor of the central nervous system. The standard treatment method is microsurgical removal of the tumor followed by chemotherapy and radiation therapy. However, due to the malignant nature of the tumor, treatment results are unsatisfactory and continued tumor growth (relapse) is inevitable. This article reports the results of surgical treatment of primary and relapsed growth of glioblastomas of the cerebral hemispheres who received inpatient treatment at the Republican Specialized Scientific Practical Medical Center of Neurosurgery.
References
Epidemiology of Intracranial Gliomas / T. Quinn [et al.] //Prog. Neurol. Surg. Basel. — 2018. — Vol.30. — P.1–11.
The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary / D. N. Louis [et al.] // Acta Neuropathol. — 2016 [Electronic Resource]. — Mode of access: DOI 10.1007/s00401-016-1545-1. — Date of access:09.03.2018.
Fuller G.N/, Scheithauer B/W. The 2007 Revised World Health Organization (WHO) Classification of Tumours of the Central Nervous System: Newly codified entities // Brain pathology. – 2007. – Vol. 17. – P. 304–307
Perrini P, Gambacciani C, Weiss A, Pasqualetti F, Delishaj D, Paiar F, Morganti R, Vannozzi R, Lutzemberger L (2017) Survival out- comes following repeat surgery for recurrent glioblastoma: a single- center retrospective analysis. J Neuro-Oncol 131:585–591.
Pinsker M, Lumenta C (2001) Experiences with reoperation on recurrent glioblastoma multiforme. Zentralbl Neurochir 62:43–47.
Prabhu VC, Barton KP, Walsh S, Borys E, Melian E (2017) Recurrent malignant gliomas: treatment options and their effect on patient’s quality of life. World Neurosurg 103:906–910.
Quick J, Gessler F, Dutzmann S, Hattingen E, Harter PN, Weise LM, Franz K, Seifert V, Senft C (2014) Benefit of tumor resection for recurrent glioblastoma. J Neuro-Oncol 117:365–372.
