A MODERN VIEW TO OPTIMIZE THE DIAGNOSIS OF THE COURSE OF PARKINSON'S DISEASE
Keywords:
Parkinson's disease, patient disability, neuroprotective therapy, long-term markers, black substanceAbstract
Parkinsonism is one of the most significant problems in clinical neurology, both due to its high prevalence in the world's populations and due to the significant disability of patients. The paper analyzes the diagnosis of Parkinson's disease (as well as other neurodegenerative diseases) at the prodromal stage. An overview of the methods of preclinical and early clinical diagnosis of BP shows that the study of the prmodromic markers and the criteria of the Premotor Phase Phase of the BP will allow in the future to significantly change the course of the disease using neuroprotective therapy at the stage preceding the death of a significant number of dopaminergic neurons of the Black Substance.
References
Захаров В.В. Нервно-психические нарушения: диагностические тесты / В.В.Захаров, Т.Г. Вознесенская – М.: МЕД пресс-информ, – 2013 – с.315.
Левин О.С. Диагностика и лечение деменции в клинической практике / О.С. Левин– М.: МЕДпресс-информ, – 2017. – с.254.
Литвиненко И.В. Нейровизуализация в диагностике нозологических форм паркинсонизма и возможности прогнозирования течения болезни Паркинсона /И.В. Литвиненко, М.М. Одинак, А.Г. Труфанов, В.А Фокин, И.В.Бойков //Болезнь Паркинсона и расстройства движений. под ред. С.Н.Иллариошкина, О.С.Левина. – НЦН РАМН – 2012. – с.113-130. 178
Jurayev A.M., Khalimov R.J. New methods for surgical Treatment of Perthes Disease in children International Journal of Psychosocial Rehabilitation, Vol 24, Issue 02, 2020. Р.301-307
Braak H. Staging of brain pathology related to sporadic Parkinson's disease / Braak H., Del Tredici K., Rüb U., de Vos R.A.I., Jansen Steur E.N.H, Braak // Neurobiol Aging.–2003–Vol.24–р.197–210.
Nombela C. Genetic impact on cognition and brain function in newly diagnosed Parkinson’s disease: ICICLE-PD study / Nombela C., Rowe J.B., Winder-Rhodes S.E., Hampshire A., Owen A.M., Breen D.P., et al. //Brain. – 2014. – Vol. 137. – 2743-58.
A.M. Jurayev, R.J. Khalimov New methods for surgical Treatment of Perthes disease in children International Journal of Psychosocial Rehabilitation, Vol 24, Issue 02, 2020 ISSN: 1475 -7192. 301-307.
Otero J. L. Dementia with Parkinson’s disease Clinical diagnosis, neuropsychological aspects and treatment Dementia /Otero J. L. // Neuropsychologia –2018 – December –2(4) – р.261-266
R. Dj. Khalimov, A.M. Djurayev, Kh. R. Rakhmatullayev. Rehabilitation Program For Children Withperthes Disease. Turkish Journal of Physiotherapy. and Rehabilitation. 32(3).2021. Р.18403 – 18406
Reid W.G.J. Dementia in Parkinson’s disease: a 20-year neuropsychological study (Sydney Multicentre Study) / Reid W.G.J., Hely M. A., Morris J. G. L.,Loy C., Halliday G. //J Neurol Neurosurg Psychiatry. – 2011. – Vol.82. – p. 1033.
Xu Y. Meta-analysis of risk factors for Parkinson's disease dementia.A 10-year study of the incidence of and factors predicting dementia in Parkinson’s disease / Xu Y., Yang J., Shang H. // Тranslational Neurodegeneration [Transl Neurodegener] – 2016 – Jun 01 –Vol. 5 –p. 11.
Khaydarova D.K., Mansurova N.A. Analysis of Motor Complications in Parkinson’s Disease Phenotypes. Journal of Advances in Medicine and Medical Research. 25(5): 1-7, 2018;
Khodjieva D. T., Khaydarova D. K. Diagnosis and Treatment of early stage parkinson's disease. European Journal of Research. № 9-10 (9-10), 2017.Vienna, Austria.
Khodjieva D.T., Khaydarova D.K. Clinical features of vertical sight disorders in patients with parkinson’s disease. Journal of Research in Health Science 1 (2) issue 2018
Толибов Д.С. Рахимбаева Г.С. Особенности диагностики и терапии болезни Альцгеймера и сосудистой деменции. Бюллетень ассоциации врачей Узбекистана.2019, С.65-70.
Хакимова С.А. Даминова Х.М. Корреляция болезни Паркинсона с уменьшенным риском гипертензии. Журнал неврология. №4 (76). 2018. С.103
Даминова Х.М., Абдуллаева Н.Н., Азизова Р.Б. Болезнь Паркинсона и синдром паркинсонизма. Методическое пособие, 2019 г
D.Akramova., G. Rakhimbaeva. Role of increased levels of endothelial factors in cognitive impairment in the Parkinson’s disease and vascular parkinsonism. Journal of the Neurological Sciences World Congress on Neurology, 2019, Vol.405, p.296.
Akramova D. Rakhimbaeva G. Kuranbaeva S. Effective diagnostic and treatment methods in vascular parkinsonism and Parkinson’s disease: Temporhythmal correction. XXIII World Congress on Parkinson‘s Disease and Related Disorders.Lyon, France, 19 – 22 August 2018 P-142
Daminova H.M., Abdullaev B. Development and practical care of poststroke Parkinson s disease. Материалы научно практической конференции с международным участием «Инновации в клинической неврологии». Журнал Неврологии №4. 2017. С.64
