GENETIC FACTORS FOR DIABETIC POLYNEUROPATHY IN PATIENTS WITH TYPE I – DIABETES
Keywords:
genetic factors, type I diabetes, diabetic polyneuropathyAbstract
The results of the study justify the need to conduct ENMG, quantitative sensory and autonomous testing when examining patients with type I- diabetes in the early stages of the disease, which is important for prescribing timely treatment at the subclinical stage. It was found that the study of the lipid spectrum, as well as the identification of late complications of diabetes (retinopathy) can be used in clinical practice to determine the presence of risk factors for the development of DPN severity. The results of the study allow us to develop recommendations for identifying patients with a subclinical stage of neuropathy.
References
Danyang Guo, Hiroki Mizukami, Sho Osonoi, Kazuhisa Takahashi, Soroku Yagihashi Beneficial effects of combination therapy of canagliflozin and teneligliptin on diabetic polyneuropathy and β-cell volume density in spontaneously type 2 diabetic Goto-Kakizaki rats Metabolism In press, journal pre-proofAvailable online 14, April 2020, Article 154232
Alon Abraham, Ari Breiner, Carolina Barnett, Hans D. Katzberg, Vera Bri Uric acid levels correlate with the severity of diabetic sensorimotor polyneuropathy Journal of the Neurological Sciences Volume 37915, August 2017, Pages 94-98
Alyce S. Adams, Brian Callaghan, Richard W. Grant Overcoming barriers to diabetic polyneuropathy manageme nt in primary care Healthcare Volume 5, Issue 4, December 2017, Pages 171-173
Cinzia Ciccacci, Andrea Latini, Carla Greco, Cristina Politi, Vincenza Spallone Association between
a MIR499A polymorphism and diabetic neuropathy in type 2 diabetes Journal of Diabetes and its Complications Volume 32, Issue 1, January 2018, Pages 11-17
Cristina Politi, Cinzia Ciccacci, Cinzia D’Amato, Giuseppe Novelli, Vincenza Spallone Recent advances in exploring the genetic susceptibility to diabetic neuropathy Diabetes Research and Clinical Practice Volume 120, October 2016, Pages 198-208
Kris Rutten, Stacey A. Gould, Luke Bryden, Henri Doods, Anton Pekcec Standard analgesics reverse burrowing deficits in a rat CCI model of neuropathic pain, but not in models of type 1 and type 2 diabetes-induced neuropathic pain Behavioural Brain Research Volume 35017, September 2018, Pages 129-138
Solomon Tesfaye Neuropathy in diabetes Medicine Volume 47, Issue 2, February 2019, Pages 92-99
Alexey G. Nikitin, Dariya A. Chudakova, Igor A. Strokov, Tamara
R. Bursa, Valery. V. Nosikov Leu54Phe and Val762Ala polymorphisms in the poly (ADP-ribose) polymerase-1 gene are associated with diabetic polyneuropathy in Russian typ e 1 diabetic patients Diabetes Research and Clinical Practice Volume 79, Issue 3, March 2008, Pages 446-452
M. Niesters, P. L. Proto, L. Aarts, E. Y. Sarton, A. Dahan Tapentadol potentiates descending pain inhibition in chronic pain patients with diabetic polyneuropathy British Journal of Anaesthesia Volume 113, Issue 1, July 2014, Pages 148-156
Jacek Kasznicki, Agnieszka Sliwinska, Marcin Kosmalski, Anna Merecz, Jozef Drzewoski Genetic polymorphisms (Pro197Leu of Gpx1, +35A/C of SOD1, −262C/T of CAT), the level of antioxidant proteins (GPx1, SOD1, CAT) and the risk of distal symmetric polyneuropathy in Polish patients with type 2 diabetes mellitus Advances in Medical Sciences Volume 61, Issue 1, March 2016, Pages 123-129
Seydahmet Akın, Cem Bölük, Ülkü Türk Börü, Mustafa Taşdemir, Özcan Keskin Restless legs syndrome in type 2 diabetes mellitus Primary Care Diabetes Volume 13, Issue 1, February 2019, Pages 87-91
Gordon Sloan, Pallai Shillo, Dinesh Selvarajah, Jing Wu,Solomon Tesfaye A new lookat painfuldiabeticneuropathy Diabetes Research and Clinical Practice Volume 144, October 2018, Pages 177-191
Alon Abraham, Carolina Barnett, Hans D. Katzberg, Leif E. Lovblom, Vera Bril Nerve function varies with hemoglobin A1c in controls and type 2 diabetes Journal of Diabetes and its Complications Volume 32, Issue 4, April 2018, Pages 424- 428
Matti D. Allen, Kurt Kimpinski, Timothy J. Doherty, Charles
L. Rice Length dependent loss of motor axons and altered motor unit properties in human diabetic polyneuropathy Clinical Neurophysiology Volume 125, Issue 4, April 2014, Pages 836-843
Antioxidant protection system in the model of experimental diabetes Mukhammad Mustafakulov, Tohir Ishanhodzhaev, Talat Saatov Journal of Biomedicine and Practice 2018-3- 6–10. http://dx.doi.org/10.26739/2181-9300-2018-3-1
Khalidjan Komilov, Nargiza Normatova, Nodira Alikhanova Epidemiological aspects of diabetic retinopathy in Uzbekistan Journal of Biomedicine and Practice 2019-3- 11-19 ht tp:/10.26739/2181-9300-2019-3-1
