СLINICAL AND ELECTRONEUROPHYSIOLOGICAL FEATURES OF PATIENTS WITH MIGRENOUS CEPHALGIA COMORBID WITH EPILEPSY

Abstract

The estimated prevalence of headache in adults (with clinical manifestations at least once during the past year) is about 50%. Between half and three quarters of people aged 18-65 worldwide have had headaches in the past year, and more than 30% of these people have reported migraines. 1.7 - 4% of the world's adult population suffers from headaches lasting 15 days or more each month. Despite regional differences, headaches are a worldwide problem that affects people regardless of age, race, income level and geographic area. In the Global Burden of Disease Survey, which was updated in 2013, migraine is ranked sixth among the causes associated with years of disability (YLD). Headaches generally rank third among such causes. Until now, the diagnosis of migraine is exclusively clinical, and any diagnostic tests are aimed only at excluding other causes of headache (Osipova, 2010). Accordingly, the search for migraine biomarkers, confirming this diagnosis, and not refuting others, is the leading vector in this scientific direction. [1]