PREVALENCE AND NEUROLOGICAL FEATURES OF DIABETIC POLYNEUROPATHY IN TYPE 1 DIABETES
Keywords:
type I diabetes, diabetic polyneuropathy, neurological featuresAbstract
The results of analysis show a statistically significant correlation between the NIS LL scores and the duration of the disease; however, no correlation was found between the glycated hemoglobin level and the NIS LL scores. At stages 2 and 3 of DPN, 77.5% of patients had positive neuropathic symptoms according to the TSS scale. Most often, patients complained of numbness in the feet area 28.6%, complaints of pain in the legs were presented in 26.9%, complaints of burning in the feet area - 21.2%, complaints of paresthesia in the feet - 15.8% of patients. In type 1 diabetes, the prevalence of DPN was 68.3%, of which subclinical DPN - in 46.8%, symptomatic DPN - in 22.5%. With a duration of diabetes up to 5 years, symptomatic DP is detected in 6% of patients, with a duration of diabetes from 5 to 10 years in 14.7% of patients, with a duration of diabetes of more than 10 years in 37.8% of patients.
References
Alon Abraham, Ari Breiner, Carolina Barnett, Hans D. Katzberg, Vera Bri Uric acid levels correlate with the severity of diabetic sensorimotor polyneuropathy// Journal of the Neurological Sciences Volume 37915, August 2017, Pages 94-98
Alyce S. Adams, Brian Callaghan, Richard W. Grant // Overcoming barriers to diabetic polyneuropathy manageme nt in primary care Healthcare Volume 5, Issue 4, December 2017, Pages 171-173
Biryukova E., Gannenkova E., Solovieva I. Diabetic polyneuropathy: what have we achieved in understanding the problem? // RIJ, 2020 №3. Pp. 14-16
Cinzia Ciccacci, Andrea Latini, Carla Greco, Cristina Politi, Vincenza Spallone //Association between a MIR499A polymorphism and diabetic neuropathy in type 2 diabetes Journal of Diabetes and its Complications Volume 32, Issue 1, January 2018, Pages 11-17
Cristina Politi, Cinzia Ciccacci, Cinzia D’Amato, Giuseppe Novelli, Vincenza Spallone //Recent advances in exploring the genetic susceptibility to diabetic neuropathy Diabetes Research and Clinical Practice Volume 120, October 2016, Pages 198-208
Danita Weeracharoenku, Signe Toft Andersen, Supranee Niruthisard. Painful and non-painful diabetic polyneuropathy: Clinical characteristics and diagnostic issues / // J Diabetes Investig 2019.Vol. 10. No. 5. Р.1148-1155.
Kris Rutten, Stacey A. Gould, Luke Bryden, Henri Doods, Anton Pekcec //Standard analgesics reverse burrowing deficits in a rat CCI model of neuropathic pain, but not in models of type 1 and type 2 diabetes-induced neuropathic pain Behavioural Brain Research Volume 35017, September 2018, Pages 129-138
Loban D., Bychik M., Usova N. Clinical characteristics of patients with diabetic polyneuropathy // Actual problems of medicine. 2020.No. 21. S. 48-49.
Maher R. Khdour. Treatment of diabetic peripheral neuropathy: a review Pharmacotherapy // Journal of Pharmacy and Pharmacology. Pharmaceutical Society, 2020. No.72. Р. 863–872.
Sandra Sif Gylfadottira, Diana Hedevang, Sia Kromann Nicolaisenc, Henning Andersena. Diabetic polyneuropathy and pain, prevalence, and patient characteristics: a cross-sectional questionnaire study of 5,514 patients with recently diagnosed type 2 diabetes // 2020 Volume 161 Number 3. Р 575-576.
