COMPARATIVE ANALYSIS OF THE EFFECTIVENESS OF COMPLEX TREATMENT OF OPTIC NEUROPATHY OF VARIOUS GENESIS

Authors

  • Sayyora Saidaminova Agzamova
  • Mirkamol Nuraliyevich Hikmatov
  • Olimjonova Farangiz Jasur qizi

Keywords:

глаукоматоз оптик нейропатия, травматик оптик нейропатия, нейропротекция, Мексидол, микроциркуляция

Abstract

Relevance. The main significance of the decrease in vision and atrophy of the optic nerve in traumatic optic neuropathy (TON) and glaucomatous optic neuropathy (GON) is assigned to vascular changes in the blood supply system of the optic nerve and retina. Purpose of the study. To determine the effectiveness of complex neuroprotective treatment of patients with GON and TON based on functional and hemodynamic parameters. Material and methods. We examined 22 patients (33 eyes) diagnosed with primary open-angle glaucoma (POAG) with compensated intraocular pressure (IOP) and 20 patients (20 eyes) previously operated on with various fractures of the midface bones (MFF) with TON. Complex treatment included: Ethylmethylhydroxypyridine succinate 50 mg (Mexidol is dissolved in 100 ml - 0.9% sodium chloride solution) intravenously for 10 days, Lyophilisate 10 mg - 2.0 ml (Cortexini was dissolved in 0.5 ml of 0.5% solution Novocaine) at a dose of 0.5 ml, which was administered parabulbarno for 10 days. Results and conclusion. The proposed scheme of drug prevention of TON and GON leads to stable preservation of visual functions, improvement of hemodynamic parameters (83%).

References

Агзамова С.С. Совершенствование диагностики и лечения офтальмологических осложнений при скулоорбитальных травмах. Международный научно-практический журнал «Офтальмология. Восточная Европа». 2021;11.3:311-320. [Agzamova S.S. Improving the diagnosis and treatment of ophthalmic complications in zygomatic-orbital injuries. International scientific and practical journal “Ophthalmology. Eastern Europe". 2021;11.3:311-320. (In Russia)]. https://doi.org/10.34883/PI.2021.11.3.030

Published

2026-03-25