SCIENTIFIC ANALYSIS OF RADIOMORPHOLOGIC CORRELATIONS BETWEEN HISTOMORPHOLOGICAL ALTERATIONS AND MODERN NEUROIMAGING DATA IN TRAUMATIC BRAIN INJURY

Authors

  • Mamazhanov Bokhadirjon Solizhanovich
  • Norov Abdurakhmon Ubaydulloevich
  • Kholikov Shavkatbek
  • Alibekov Omadbek Ozodbekovich

Keywords:

traumatic brain injury, histology, MRI, CT, hemorrhage, radiomorphologic correlation

Abstract

This study investigates the correlation between histological alterations and modern neuroimaging findings (MRI and CT) in traumatic brain injury (TBI). Autopsy and imaging data of 40 patients (2023–2024) were analyzed. Histological examination revealed parenchymal hemorrhages, brain edema, neuronal dystrophy, and venous congestion. MRI/CT findings showed hematomas, mass effect, and intracranial hypertension with an overall radiomorphologic concordance of 77%. The strongest correlations were observed for hemorrhage (ρ=0.86) and edema (ρ=0.79). The results demonstrate that combined histologic and imaging analysis is crucial for accurate diagnosis, prognosis, and understanding of brain injury pathogenesis.

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Published

2025-11-19