MODERN PERSPECTIVES ON THE CHARACTERISTICS AND RISK FACTORS OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY IN CHILDREN (Literature Review)
Keywords:
children, progressive multifocal leukoencephalopathy, risk factors, neurodegenerative diseasesAbstract
Progressive multifocal leukoencephalopathy (PML) has always been among the urgent issues in neurology and pediatrics, both in research and practice. In particular, neurological practice deals significantly with conditions leading to severe health disorders and disability in children due to the demyelination process caused by the JC virus (John Cunningham virus). According to official data, in Uzbekistan, cases of this type of disease rank second after neurodegenerative diseases in the structure of childhood disability.
References
Åström, K. E. Progressive multifocal leukoencephalopathy: a hitherto unrecognized complication of chronic lymphatic leukaemia and Hodgkin's disease / K. E. Åström, E. L. Mancall, E. P. Richardson // Brain. – 1958. – Vol. 81, № 1. – P. 93–111.
Richardson, K. Progressive multifocal leukoencephalopathy in children: clinical and radiological features / K. Richardson, S. M. Peters // Pediatric Neurology. – 1995. – Vol. 12, № 3. – P. 207–212.
Berger, J. R. Progressive multifocal leukoencephalopathy and the spectrum of JC virus-related disease / J. R. Berger, L. Houff // Nature Reviews Neurology. – 2019. – Vol. 15, № 6. – P. 313–327.
Cortese, I. Progressive multifocal leukoencephalopathy and the spectrum of JC virus-related neurological disease / I. Cortese, D. S. Reich // Nature Reviews Neurology. – 2021. – Vol. 17, № 1. – P. 37–51.
Gheuens, S. Progressive multifocal leukoencephalopathy in individuals with minimal or occult immunosuppression / S. Gheuens, G. Pierone, P. Peeters // Journal of Neurovirology. – 2020. – Vol. 26, № 1. – P. 1–18.
Williamson, E. M. JC virus infection in the setting of prophylactic treatment of multiple sclerosis / E. M. Williamson, J. R. Berger // Multiple Sclerosis Journal. – 2018. – Vol. 24, № 6. – P. 737–744.
Brew, B. J. Progressive multifocal leukoencephalopathy after natalizumab therapy: clinical and MRI course / B. J. Brew, S. J. Davies, P. Cinque // Annals of Neurology. – 2020. – Vol. 87, № 5. – P. 671–685.
Miskin, D. P. Diagnosis of Progressive Multifocal Leukoencephalopathy: comparative analysis of cerebrospinal fluid and plasma JC virus PCR assays / D. P. Miskin, R. Koralnik // Journal of Infectious Diseases. – 2019. – Vol. 219, № 7. – P. 1057–1067.
Monaco, M. C. JC virus infection of meningeal and choroidal epithelial cells in patients with progressive multifocal leukoencephalopathy / M. C. Monaco, B. E. Sabath, L. M. Durham // Journal of Virology. – 2018. – Vol. 92, № 17. – P. e00275-18.
DT Hodzhieva, SS Pulatov, DK Hajdarova Vse o gemorragicheskom insul'te lic pozhilogo i starcheskogo vozrasta (sobstvennye nabljudenija) [All of hemorrhagic stroke in elderly persons (own observations)]. Nauka molodyh (Eruditio Juvenium)[Science of the young (Eruditio Juvenium)]. 2015. 87-96
Schwab, N. PML risk stratification using anti-JCV antibody index and L-selectin / N. Schwab, C. Schneider-Hohendorf, H. Wiendl // Multiple Sclerosis Journal. – 2020. – Vol. 26, № 14. – P. 1848–1858.
European Federation of Neurological Societies. EFNS guidelines on diagnosis and management of progressive multifocal leukoencephalopathy / EFNS Scientific Panel on Infectious Diseases // European Journal of Neurology. – 2019. – Vol. 26, № 6. – P. 854–865.
Вклад авторов
Ниязов Шухрат Тоштемирович внеc основной вклад в разработку концепци статьи, подготовил текст, и согласен принять на себя ответственность за все аспекты клического наблюдения. Худойбердиева Диловар Имомназарова участвовала в разработке концепции статьи и подготовке текста, а также принимали активное участие в лечение пациента, подготовки материалов и описании клинического наблюдения. Все авторы одобрили окончательную версию публикации.
Муаллифларнинг ҳиссалари
Ниёзов Шуҳрат Тоштемирович мақола концепциясини ишлаб чиқишга асосий ҳисса қўшди, матнни тайёрлади ва клиник кузатувнинг барча жиҳатлари учун масъулиятни ўз зиммасига олишга рози. Худойбердиева Диловар Имомназарова мақола концепциясини ишлаб чиқиш ва матнини тайёрлашда иштирок этди, шунингдек, беморни даволаш, материалларни тайёрлаш ва клиник кузатувни тавсифлашда фаол иштирок этди. Барча муаллифлар нашрнинг якуний версиясини маъқулладилар.
AUTHORS CONTRIBUTIONS
Shuhrat Toshtemirovich Niyazov made the main contribution to the development of the article's concept, prepared the text, and agrees to assume responsibility for all aspects of clinical observation. Xudoyberdiyeva Dilovar Imomnazarova participated in developing the article's concept and preparing the text, as well as actively participated in patient treatment, preparing materials, and describing clinical observation. All authors approved the final version of the publication.
