CLINICAL CASE: CEREBRAL AMYLOID ANGIOPATHY AND NORMOTONIC HYDROCEPHALUS

Authors

  • Saydaliev Saidaziz Bakhtiyor ugli

Keywords:

normotensive hydrocephalus, cerebral amyloid angiopathy, cognitive dysfunctions, MRI

Abstract

This clinical case aims to remind general practitioners, urologists, therapists, traumatologists, orthopedists, neurosurgeons, and neurologists of the need for a more serious approach to patients presenting with movement disorders, urinary incontinence, and cognitive impairment. Early diagnosis of normotensive hydrocephalus and cerebral amyloid angiopathy timely referral to the appropriate specialist can improve patient's quality of life and prevent early disability. The following clinical case presents a patient with comorbidity of normotensive hydrocephalus and cerebral amyloid angiopathy based on laboratory and instrumental examinations. The analysis results highlight the need for a deeper study of this condition and emphasize the importance of providing physicians with relevant information.

References

Гисматуллина Э.И., Токарева Н.В., Есин Р.Г. Нормотензивная гидроцефалия. Клиническое наблюдение // Практическая медицина. — 2012. — 2(57). — С. 192-194

Дамулин И.В. Вторичные деменции (когнитивные расстройства при травматических и опухолевых поражениях головного мозга, при инфекционных и аутоиммунных заболеваниях): Методическое пособие для врачей. — М.: ММА им. И.М. Сеченова, 2009. — С. 9-14.

Cerebral amyloidosis, amyloid angiopathy, and their relationship to stroke and dementia. Jorge Ghiso and Blas Frangione Department of Pathology, New York University School of Medicine, New York, NY, USA. J Alzheimers Dis. 2001 Feb;3(1):65-73.

Gallia G.L., Rigamonti D., Williams M.A. The diagnosis and treatment of idiopathic normal pressure hydrocephalus // Nat. Clin. Pract. Neurol. — 2006. — 2. — P. 375-381.

Mariel G Kozberg, A practical approach to the management of cerebral amyloid angiopathy Mariel G Kozberg, Valentina Peros and Susanne J van Veluw. 2021 Jun;16(4):356-369 Int. J of Neurology.

Relkin N., Marmarou A., Klinge P., Bergsneider M., Black P.M. Diagnosing — idiopathic normal-pressure hydrocephalus // Neurosurgery. — 2005. — 57(3). — P. 4-16.

S. Schiavolin, G. Camarda, A. Mazzucchelli, Cognitive and psychological characteristics in patients with Cerebral Amyloid Angiopathy: a literature review, Neurological Sciences. – 2024. − Vol. 45, №7. – Pp. 3031-3049

Sharma, M.J. Cerebrovascular and neurodegenerative pathologies in long term stable mild cognitive impairment / M.J. Sharma, B.L. Callahan // J Alzheimers Dis.− 2021. − Vol. 79, № 3. – Pp. 1269-1283.

Published

2025-06-26