STATE OF APUDOCYTES IN THE LUNGS IN BRONCHIOECTATIC DISEASE

Authors

  • Abdullaev Bakhtiyor Saidovich
  • Xamidova Farida Muinovna
  • Islamov Shavkat Eryigitovich
  • Norjigitov Azamat Musakulovich
  • Makhmatmuradova Nargiza Negmatullaevna

Keywords:

lungs, bronchiectasis, children, condition of apudocytes

Abstract

The results of the study indicate that apudocytes are also involved in the pathogenesis of diseases. Morphological changes - hyperplasia of goblet cells and bronchial glands, discoordination of secretion and mucociliary transport. characterize various manifestations of pathology in bronchiectasis. In the future, inflammatory changes join with infiltration of the bronchial wall by lymphocytes, macrophages and other cellular elements. Granulation tissue, hypertrophy of muscle bundles, perivascular sclerosis gradually increase, and later fibrosis of the muscular layer of the bronchus. In violation of the structure of the epithelium and the absence of endocrine cells in it, the processes of immunogenesis proceed under the epithelium. The appearance of numerous plasmocytes indicates an intense efferent phase of the development of immunity.

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Published

2023-01-31