PROGNOSTIC SIGNIFICANCE OF INTESTINAL DYSBIOSIS ON THE COURSE OF ACUTE BRONCHIOLITIS IN CHILDREN

Abstract

To study the intestinal microflora in acute bronchiolitis in children in order to predict the severity of the disease and prevent relapses. 54 children with acute bronchiolitis were examined. Anamnestic, clinical, laboratory, immunological and bacteriological data were studied. Acute bronchiolitis in children was severe with the development of acute broncho-obstruction and respiratory failure of varying severity, which required treatment in intensive care. In addition to the main predictors of the formation of acute bronchiolitis and the development of repeated episodes of broncho-obstruction in early childhood (anemia in mothers in the antenatal period, prematurity, cold period of the year, absence or short duration of breastfeeding, early onset of respiratory infections in the first year of life, early clinical manifestations of broncho-obstruction, the presence accompany diseases, a combination of allergic anamnesis), the development of microbial imbalance and bacterial colonization of the intestine has been identified, which should be taken into account when choosing treatment tactics and preventing the progression of the disease.