COVID-19 ДАН СУНГ БЕМОРЛАРДА УГЛЕВОД АЛМАШИНУВИ БУЗИЛИШЛАРИНИНГ ТАРҚАЛИШИ
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COVID-19, 1 тур қандли диабет, 2 тур қандли диабет, коронавирус##article.abstract##
Асослаш. COVID-19 пандемияси даврида қандли диабет (КД) ва 2019 йилги COVID-19 коронавирус касаллиги ўртасида икки томонлама ўзаро таъсир мавжудлиги кўрсатилди. Бир томондан, қандли диабет билан оғриган беморларда ўлим хавфи ёки реанимация бўлимида COVID-19ни даволашда асоратлар, шунингдек, диабетсиз одамларга нисбатан COVID-19 билан боғлиқ асоратлар юқори. Бошқа томондан, ҳозирги вақтда клиник маълумотлар шуни кўрсатадики, коронавируёснинг оғир ўткир респиратор синдроми метаболизмнинг дисрегулятсиясига ва глюкоза гомеостазининг бузилишига олиб келиши мумкин.
Мақсад. COVID-19 билан касалланган беморларда қандли диабетнинг янги ҳолатларининг таҳлил қилиш, қандли диабет билан касалланган ва диабет бўлмаган беморларда клиник натижалар ва қўшма касалликларни таққослаш.
Усуллари. моноцентрал кузатув тадкикотида 267 киши иштирок этди, улар гурухларга булинди: янги аникланган диабетга чалинган беморлар, 1 ва 2 тур диабетга чалинган беморлар, углевод алмашинувининг бузилиши булмаган беморлар. Беморларнинг ўрта yoshi 51,3 ёшни ташкил етди. Углевод алмашинувининг бузилишини текшириш учун барча беморлар қонида глюкоза текширувидан ўтдилар. Шунингдек, касалликларни баҳолаш учун анамнез, клиник текширув, қон босими, юрак уриш тезлиги, БМИ параметрларини ўлчаш ҳам ўтказилди.
Натижалар. 267 бемордан 44,9% беморларда углевод алмашинувининг бузилиши аниқланган, 23,9% янги аникланган диабет, 18,7% кандли диабет 2 тур, 2,2% кандли диабет 1 турга чалинган. Маълумотларни таҳлил қилгандан сўнг, углевод алмашинуви бузилган беморларда касалликнинг прогнози ва натижалари ёмонроқ еканлиги аниқланди.
Хулоса. COVID-19 глюкоза гомеостазини дисрегуляцияга олиб келади, бу еса гипергликемия ва қандли диабет ривожланишига олиб келади. Углевод алмашинуви бузилган беморларда CОВИД-19 нинг натижалари оғиррок. Вазиятнинг оғирлиги, реанимация бўлимида касалхонага ётқизиш каби кўрсаткичлар қандли диабет ва қўшма касалликлар билан оғриган беморларда енг юқори кўрсаткичдир
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