REDUCING THE INCIDENCE OF POSTOPERATIVE COGNITIVE DYSFUNCTION IN WOMEN UNDERGOING CESAREAN SECTION DURING SPINAL ANESTHESIA AND DRUG SEDATION WITH DESMEDETOMIDINE
Keywords:
Postoperative cognitive dysfunction, spinal anesthesia, sedation, pregnancy, dexmedetomidine, cesarean sectionAbstract
The issue of cognitive dysfunction following surgical procedures and anesthesia is a focal point of current anesthesiology discourse. The occurrence of cognitive deficits post-surgery represents a widespread and unwelcome outcome, sparking a surge in scholarly research on the topic. The syndrome of postoperative cognitive dysfunction (POCD) encompasses the deterioration of advanced mental functions arising post-surgery, attributed to both the surgical intervention and the anesthesia, as defined by L.S. Rasmussen. This condition emerges early in the postoperative phase and may linger, characterized by diminished memory, challenges in attention focus, and disruption of other superior cortical functions like thought and speech, as evidenced by neuropsychological assessments. Furthermore, the direct toxic impact of anesthetic agents on cognitive abilities has been highlighted in several studies.
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Статья поступила в редакцию 04.01.2024; одобрена после рецензирования 18.02.2024; принята к публикации 20.02.2024.
The article was submitted 04.01.2024; approved after reviewing 18.02.2024; accepted for publication 20.02.2024.
Информация об авторах;
Худойбердиева Гулрух Собиржоновна – Ассистент кафедры Анестезиологии, реанимации и неотложной медицины. Самаркандский государственный медицинский университет, Самарканд, Узбекистан. Е-mail:xudoyberdievagulruh@gmail.com, https://orcid.org/0009-0002-7385-363X
Источники финансирования: Работа не имела специального финансирования.
Конфликт интересов: Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.
Вклад авторов:
Худойбердиева Г.С.− сбор и анализ источников литературы, написание текста.
Information about the authors:
Khudoiberdieva Gulrukh Sobirjonovna – Assistant of the Department of Anesthesiology, Reanimation and Emergency Medicine. Samarkand State Medical University, Samarkand, Uzbekistan. (hidden) https://orcid.org/0009-0002-7385-363X
Sources of funding: The work did not have special funding.
Conflict of interest: The authors declare that there are no obvious or potential conflicts of interest related to the publication of this article.
Authors' contributions:
Khudoiberdieva G.S. − collection and analysis of literature sources, writing the text.