CLINICAL COURSE IN CERTAIN HISTOLOGICAL VARIANTS OF BREAST CARCINOMA
Keywords:
breast cancer, tumor, morphology, paget's cancer, 5-year survival rateAbstract
Purpose: To determine the prognosis of survival depending on the histological variant of breast cancer.
Methods: For the study, personal observations of patients, analysis of case histories and outpatient records of patients treated in the Samarkand branch of the RSNPMTSOIR from 2017 to 2022 were used. During this time, 1,650 patients with primary breast cancers were treated.
Results of the study: Depending on the stage of the process in Paget breast cancer, patients were distributed as follows: I T1, 2 N0M0 in 6, IIa T2N0M0 in 13, IIB, T2N1M0 in 5, IIIa T3N0M0 in 4, IIIB, T1,2,3 N1,2 M0 in 6.
In the clinical examination of patients, the tumors had a bumpy surface and a dense consistency, 2 patients had dense enlarged axillary lymph nodes. 7 patients had I-IIa, T2N0M0 stage of the prevalence of the process, 2-IIIb, T2-3 N1-2 M0. The frequency of metastasis was 16.5%, information on 5-year survival is available for 2 patients, the rest of the patients continue to be monitored.
Extracts: The most common histological form (50%) was Paget's cancer, characterized by a slow course, high 3 and 5-year survival of patients with locally common processes.
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