COMPARATIVE ANALYSIS OF SEDATION WITH DEXMEDETOMIDINE AND PROPOFOL IN PREGNANT WOMEN DURING ABDOMINAL DELIVERY
Keywords:
Sedation, dexmedetomidine, propofol, spinal anesthesia (SA), caesarean section.Abstract
Target. To study the efficacy and safety of using dexmedetomidine to stabilize hemodynamics and arousal in pregnant women of various categories during caesarean section.
Material and methods. Under observation were 50 pregnant women aged 20 to 37 years (mean age 30.1±5.2 years), delivered by caesarean section.
Results: The study showed that there are significant differences in changes in the main hemodynamic parameters between the groups at all stages of the study. These data demonstrate greater hemodynamic stability under conditions of dexmedetomidine against the background of SA in patients of various categories of pregnant women. In the 1st group, along with a decrease in heart rate at all stages of the study, there was a short-term increase in SI and a decrease in BPmean only at the 4th stage. In the 2nd group of pregnant women during delivery under conditions of propofol against the background of SA, the most significant changes in hemodynamics occurred: BP and TPVR decreased significantly more pronounced at all stages of the operation compared with the control group.
Findings. Our results confirm that dexmedetomidine is more effective and safer than propofol in pregnant women of various categories.
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