A COMPREHENSIVE APPROACH TO THE DIAGNOSIS AND TREATMENT OF MENSTRUAL DISORDERS IN ADOLESCENT GIRLS WITH OBESITY

Authors

  • KHUDOYQULOVA Zukhra Sobir qizi
  • NASIMOVA Nigina Rustamovna

Keywords:

semizlik, o‘smir qizlar, hayz sikli buzilishi, reproduktiv salomatlik, gormonal buzilishlar, diagnostika, davolash

Abstract

Objective. To evaluate the effectiveness of modern clinical, diagnostic, and therapeutic approaches in adolescents with menstrual disorders associated with obesity and to optimize their management. Materials and Methods. The study included adolescent girls with menstrual disorders associated with obesity. Clinical examination, anthropometric assessment, hormonal and biochemical analyses, pelvic ultrasonography, and evaluation of metabolic parameters were performed. Results. Obesity was associated with significant hormonal and metabolic disturbances adversely affecting reproductive health. Comprehensive treatment resulted in improvement of clinical manifestations and laboratory parameters. Conclusion. An individualized diagnostic and therapeutic approach contributes to the normalization of menstrual function and improvement of reproductive health in adolescents with obesity.

References

World Health Organization. Adolescent obesity and related health risks. Geneva: WHO; 2024.

World Health Organization. WHO guideline on the prevention and management of obesity throughout the life course. Geneva: WHO; 2025.

International Federation of Gynecology and Obstetrics (FIGO). Good clinical practice recommendations for adolescent gynecology. Int J Gynaecol Obstet. 2023;161(Suppl 1):1–36.

American College of Obstetricians and Gynecologists. Menstruation in girls and adolescents: using the menstrual cycle as a vital sign. Committee Opinion No. 785. Obstet Gynecol. 2024;143–e12.

Peña AS, Witchel SF, Hoeger KM, et al. International evidence-based recommendations for polycystic ovary syndrome in adolescents. Hum Reprod Open. 2023;2023(4).

Teede HJ, Tay CT, Laven JSE, et al. Recommendations from the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. Fertil Steril. 2023;120(5):1006–1032.

Ibáñez L, Oberfield SE, Witchel SF, et al. An International Consortium Update: Pathophysiology, Diagnosis and Treatment of Polycystic Ovary Syndrome in Adolescence. Horm Res Paediatr. 2023;96(2):81–95.

Styne DM, Arslanian SA, Connor EL, et al. Pediatric Obesity—Assessment, Treatment, and Prevention. J Clin Endocrinol Metab. 2023;108(4)–e898.

American Academy of Pediatrics. Clinical Practice Guideline for the Evaluation and Treatment of Children and Adolescents With Obesity. Pediatrics. 2023;151(2).

Legro RS, Arslanian SA, Ehrmann DA, et al. Diagnosis and treatment of polycystic ovary syndrome: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2013;98(12):4565–4592.

Williams T, Mortada R, Porter S. Diagnosis and treatment of polycystic ovary syndrome. Am Fam Physician. 2016;94(2):106–113.

Rizaev J. A., Ashirov Z. F., Toshev S. U., Islamov N. H., Salamova L. A. [et al.]. Medical and organizational measures to improve the provision of medical care in the dermatovenerology profile // International Journal of Current Research and Review. – 2020. – Vol. 12, No. 24. – P. 120–122.

Ризаев Ж. А., Адилова Ш. Т., Пулатов О. А. Обоснование комплексной программы лечебно-профилактической стоматологической помощи населению Республики Узбекистан // Аспирант и соискатель. – 2009. – С. 73–74.

Alimdjanovich J. R., Ibragimovich A. K. Organization of monitoring of the quality of services provided for the prevention and fight against postpartum bleeding in women // Central Asian Journal of Medical and Natural Sciences. – 2021. – Vol. 2, No. 6. – P. 14–21.

Alimjanovich J. R., Agababyan L. R., Kamalov A. I. Prevention and treatment of postpartum hemorrhage // Central Asian Journal of Medical and Natural Sciences. – 2021. – Vol. 2, No. 4. – P. 204–209.

Azziz R. Polycystic ovary syndrome. Obstet Gynecol. 2018;132(2):321–336.

Министерство здравоохранения Республики Узбекистан. Клинический протокол по диагностике и лечению нарушений менструального цикла у девочек-подростков. Ташкент; 2023.

Худайкулова З.С., Насимова Н.Р. Современные клинико-диагностические подходы к ведению девочек-подростков с нарушениями менструального цикла на фоне ожирения. Материалы научно-практической конференции СамГМУ. Самарканд; 2025.

Published

2026-11-12