PERINATAL INVOLVEMENT OF CENTRAL NERVOUS SYSTEM AND ITS IMPACT ON CHILD DEVELOPMENT
Keywords:
central nervous system, perinatal involvement, developmental disorders, pediatric neurologyAbstract
In this work, the relationship between perinatal lesions of the central nervous system and neurological syndromes formed in childhood with disorders of somatic development was studied. Children and adolescents treated at the neurological rehabilitation center were selected as the object of observation. The study was conducted retrospectively based on the data of 110 children under 2 years of age, recorded at the time of hospitalization. All of them had perinatal CNS damage or associated neurological syndromes. Anthropometric indicators were assessed using z-points in accordance with statistical standards. Results: Signs of perinatal damage manifested in the developmental process of a significant number of children.
Short stature, weight deficit, and head circumference anomalies were common. In some children, macrocephaly or height was noted. Restriction of motor activity was also most often observed in children with perinatal lesions. Conclusion: Perinatal damage to the central nervous system significantly affects the process of growth and development of children. The pathology manifests itself through various disorders, hindering the child's overall quality of life and social integration. Consequently, the early detection of this pathology and the application of complex treatment methods are necessary for the health of children.
References
Kulak W, Okurowska-Zawada B, Sienkiewicz D, Paszko-Patej G, Wojtkowska M. Children with symptomatic and asymptomatic hydrocephalus: neurological and developmental status. Childs Nerv Syst. 2011;27:11951203. (in Uzb)
Rekate HL. A contemporary definition and classification of hydrocephalus. Semin Pediatr Neurol. 2009;16:915.(in Uzb)
Vinchon M, Rekate H, Kulkarni AV. Pediatric hydrocephalus outcomes: a review. Fluids Barriers CNS. 2012;9:18.(in Uzb)
De Oliveira RS, Machado HR. Pediatric hydrocephalus: what has changed since the beginning of the millennium. Einstein. 2011;9:106115.(in Uzb)
Riva-Cambrin J, Kestle JRW, Holubkov R, Butler J, Kulkarni AV, Drake J, et al. Risk factors for shunt malfunction in pediatric hydrocephalus: a multicenter prospective cohort study. J Neurosurg Pediatr. 2016;17:382390.(in Uzb)
Kulkarni AV, Drake JM, Kestle JR, Mallucci CL, Sgouros S, Constantini S. Predicting who will benefit from endoscopic third ventriculostomy compared with shunt insertion in childhood hydrocephalus using the ETV success score. J Neurosurg Pediatr. 2010;6:310315.(in Uzb)
Vinchon M, Baroncini M, Delestret I. Adult outcome of pediatric hydrocephalus. Childs Nerv Syst. 2012;28:847854.(in Uzb)
Hoppe-Hirsch E, Sainte-Rose C, Renier D, Cinalli G, Pierre-Kahn A, Hirsch JF. Late outcome of the surgical treatment of hydrocephalus. Childs Nerv Syst. 1998;14:9799.(in Uzb)
Rekate HL. The definition and classification of hydrocephalus: a personal recommendation to stimulate debate. Cerebrospinal Fluid Res. 2008;5:2.(in Uzb)
Riva-Cambrin J, et al. Hydrocephalus Clinical Research Network. Risk factors for shunt malfunction in pediatric hydrocephalus: a multicenter prospective cohort study. J Neurosurg Pediatr. 2016;17(4):382390.(in Uzb)