THE STATE OF CELLULAR IMMUNITY IN CHILDREN WITH CHRONIC DEFORMING ENDOBRONCHITIS AND BRONCHIECTASIS
Keywords:
chronic deforming endobronchitis, bronchiectasis, cellular immunity.Abstract
This article is based on the data obtained in the course of the study, as well as those available in the medical scientific literature, summarises information on the etiological factors influencing the development of diseases accompanied by chronic deforming endobronchitis and bronchiectasis. The basis for this study was the importance of cellular immunity, as immune disorders play a key role in the pathogenesis of bronchiectasis and chronic deforming endobronchitis in children. The authors examined 163 children with bronchiectasis and 82 children with chronic deforming bronchitis. Indicators of cellular immunity were determined by the modified method of Garib F.Y. (1995); Studies have shown that in the phase of exacerbation of BE and CDEB in children there are deep disorders of immune status characterized by persistent T-cell immunodeficiency. On the basis of the obtained data, the authors recommend to take into account immunologic changes when carrying out therapeutic measures.
References
Абдувалиева Ч. М. и др. Случай поздней диагностики застарелого инородного тела бронха у ребенка: научное издание // Вестник экстренной медицины. - Ташкент, 2017. - Том X N2. - C. 90-91.
Kudratova Z. E. et al. The Role of Cytokine Regulation in Obstructive Syndrome of Atypical Genesis in Children //Annals of the Romanian Society for Cell Biology. – 2021. – Т. 25. – №. 1. – С. 6279-6291.
Muhamadiyeva L. A., Kudratova Z. E., Sirojeddinova S. Pastkinafasyo’llaripatologiyasiningrivojlanishidaatipikmikrofloraningrolivazamonaviydiagnostikasi //Tadqiqotlar. Uz. – 2024. – Т. 37. – №. 3. – С. 135-139.
Kudratova Z. Pathogenetic features of bronch-obstructive syndrome in children //Результатынаучныхисследованийвусловияхпандемии (COVID-19). – 2020. – Т. 1. – №. 05. – С. 24-27.
Степанов А.А.,Бадальян А.Р. , Мельникова А.О. Бронхоэктатическая болезнь у детей. Журнал Российский вестник перинатологии и педиатрии.2018.63.(5)с.29-35
Зейтказиева С.М., Мырзамуратова А.О., Ырыскулова Ж.С., УсеноваА.О.Особенности этиологии и патогенеза бронхоэктатической болезни. ВестникКазНМУ №3, 2018, с. 128-129.
Kudratova Z. E. et al. Chlamydial infections (intracellular infection) in the development of bronchitis //TJE-Tematics journal of Education ISSN. – 2021. – С. 2249-9822.
Kudratova Z. E. et al. Modern laboratory diagnostics of M. Pneumoniae //Достижениянаукииобразования. – 2020. – №. 17. – С. 71-73.
Шамсиев А.М., Базаров Б.Б., Шахриев К.К., Алиев А.Р. Цитология бронхоальвеолярно-лаважной жидкости при гнойном эндобронхите, вызванного инородными телами бронхов у детей. //7-ежегодная Московская конференция «Гнойно-септические заболевания у детей» с участием регионов России и стран СНГ. -2-3 июня 2011. -Москва. -С.159.