CURRENT APPROACHES TO TREATMENT THE PATIENTS WITH WIDESPREAD PURULENT PERITONITIS
Keywords:
peritonitis, ozone, sodium hypochlorite solution, treatmentAbstract
Background. Treatment of disseminated peritonitis is one of the most complex and intractable problems of emergency abdominal surgery. Disseminated purulent peritonitis is a severe variant of complicated intra-abdominal infection and is a life-threatening complication of most acute surgical diseases of abdominal cavity.
Objectives. To improve the results of surgical treatment of disseminated purulent peritonitis on the basis of a differentiated approach to the choice of treatment depending on the degree of abdominal sepsis.
Materials and methods. The study is based on the results of treatment of 276 patients with widespread purulent peritonitis admitted to the surgical department of the Samarkand branch of RCEMP in the period from 2015 to 2024. Patients were conditionally divided into two groups: 132 (47.8%) patients were operated on in 2015-2019, who were included in the comparison group, and 144 (52.2%) patients were operated on from 2020 to 2024, who were included in the main group.
Results. A study of the results of combination therapy using ozonated 0.03% sodium hypochlorite solution for abdominal cavity sanitation and intravenous management in patients with abdominal sepsis showed encouraging results. There was a marked decrease in the rate of postoperative purulent inflammatory complications from 32.4% to 16.7% in SIRS - 0 and SIRS abdominal sepsis (p<0.05), and from 51.5% to 41.4% and from 70.6% to 36.0% in SIRS - 1 and SIRS - 2 abdominal sepsis (p<0.05), respectively. Fatal outcome decreased from 15.1% to 4.9% and from 41.2% to 20.0% in abdominal sepsis SIRS - 1 and SIRS - 2 (p<0.05), respectively.
Conclusions. Complex application of ozonized sodium hypochlorite solution in the postoperative period contributes to faster recovery of patients, decreased incidence of complications and improved overall clinical results.
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