ON THE ISSUE OF MORPHOLOGICAL FEATURES OF KERATODERMA IN DIABETES MELLITUS

Authors

  • KHAMIDOVA Farida Muinovna
  • NURULLAYEV Javohir Asqar o’gli

Keywords:

morphology, skin, keratoderma, diabetes mellitus

Abstract

Purpose of the study. Conducting a literary analysis taking into account the morphological features of the development of keratoderma in patients with diabetes mellitus.

Conclusion. Extensive discussion of diabetes mellitus and its impact on skin diseases such as seborrheic keratoses and keratoses pilaris, emphasizing the connection between metabolic disorders and dermatological manifestations. This is important information for understanding the complex interactions between chronic diseases and skin pathologies, and their impact on patients' overall health and quality of life.

References

Aleksandrova A.K., Smolyannikova V.A. // Insulin resistance and seborrheic keratosis Bulletin of dermatology and venereology 2015; (5): P. 73-78. (In. Russ)

Bhavani A.G., Gupta A.K. Effective utilization of databases for preventing chemical accidents // Chemical safety. - 2020. - Vol. 4. - No. 2. - P. 24-34. (In. Russ)

Dyuzhakova E., Osmanov S. Encyclopedia of clinical dermatovenereology. - Litres, 2022.

Kubanova A.A. et al. Dermatovenereology in the Russian Federation. Results of 2014. Successes, achievements. Main development paths // Bulletin of dermatology and venereology. – 2015.4. – P. 13-26. (In. Russ)

Kornisheva VG, Belova SG Etiology, clinical presentation of mycosis of the feet in patients with type 2 diabetes mellitus // Advances in Medical Mycology. – 2014. – Vol. 13. – P. 115-116. (In. Russ)

Pal'tsev MA, Potekaev NN, Kazantseva IA, et al. Clinical and morphological diagnostics of skin diseases (atlas). M: Medicine 2004; 52-53. (In. Russ)

Tsvetkova GM, Mordovtsev VN Pathomorphological diagnostics of skin diseases. Manual. M: Medicine 1986; 65-66.Ashton R., Leppard B. Differential diagnosis in dermatology. – CRC Press, 2021. (In. Russ)

Bhargava P., Mathur D. Acrochordon, diabetes and associations. Indian J Dermatol Venereol Leprol 1996; 62: P. 226—8.

Blinova S.A., Oripov F.S., Khamidovа F.M., Ismoilov J.M. Forming neuroendocrine apparatus of lung in ontogenesis // Turkish Journal of Physiotherapy and Rehabilitation; 32(2). Р. 4311-4317.

Bustan R. S. et al. Specific skin signs as a cutaneous marker of diabetes mellitus and the prediabetic state: a systematic review //Danish medical journal. – 2017. – Т. 64. – №.1. – P. A5316.

Delapp N.W., Dieckman D.K. Effect of basic fibroblast growth factor (bFGF) and insulin like growth factor I (IGF-I) and type II (IGF-II) on adult human keratinocyte growth and fibronectin secretion. J Invest Dermatol 1990; 94: P.777—80.

IJ Mardonovich. Characterization of morphological and morphometric changes in the bronchial wall in rabbits during acute experimental pneumonia he American // Journal of Medical Sciences and Pharmaceutical Research. Том 5 №6., Р. 38-46

Khamidova F.M, Blinova S.A, Ismoilov J.M. Dynamics of changes of immune and endocrine lung structures in experimental pneumonia // Journal of biomedicine and practice. №SI-2 2020. Р. 717-722.

Khamidova F.M., Blinova S.A., Ismoilov J.M. Congential and acquired struktures in the lungs of bronchiektasis disease in children. // Вопросы науки и образования. №29 (41), 2018. Р. 99-101.

Gupta T. K. et al. Endothelial dysfunction and decreased production of nitric oxide in the intrahepatic microcirculation of cirrhotic rats //Hepatology. – 1998. – Т. 28. – №. 4. – P. 926-931.

Gomez A. P. et al. Skin disorders in overweight and obese patients and their relationship with insulin //Actas Dermo-Sifiliográficas (English Edition). – 2014. – Т. 105. – №. 2. – P. 178-185.

Saraiya A., Al-Shoha A., Brodell R.T. Hyperinsulinemia associated with acanthosis nigricans, finger pebbles, acrochordons, and the sign of Leser-Trelat. Endocr Pract 2013 May-Jun; 19 (3): 522—5.

Moyer J. et al. Correlation between sweat glucose and blood glucose in subjects with diabetes //Diabetes technology & therapeutics. – 2012. – Т. 14. – №. 5. – P. 398-402.

Murphy-Chutorian B., Han G., Cohen S. R. Dermatologic manifestations of diabetes mellitus: a review //Endocrinology and Metabolism Clinics. – 2013. – Т. 42. – №. 4. – P. 869-898.

Vahora R., Thakkar S., Marfatia Y. Skin, a mirror reflecting diabetes mellitus: A longitudinal study in a tertiary care hospital in Gujarat //Indian journal of endocrinology and metabolism. – 2013. – Т. 17. – №. 4. – P. 659-664.

Samieva, G. U., Hamidova, F. М., Ismailov, J. M., & Toirova, S. B. (2020). Features Of Distribution And Density Of Lymphoid Cells Of The Mucosa Of The Larynx As A Manifestation Of Local Immunity In Chronic Laringitis (Analysis Of Sectional Material). European Journal of Molecular & Clinical Medicine, 7(03), 2020.

Sharma M. K., Sharma H. Dermatoglyphics: A diagnostic tool to predict diabetes //J Clin Diagn Res. – 2012. – Т. 6. – №. 3. – P. 327-332.

Shaheen M. A. et al. Assessment of serum leptin, insulin resistance and metabolic syndrome in patients with skin tags //Journal of the European Academy of Dermatology and Venereology. – 2012. – Т. 26. – №. 12. – P. 1552-1557.

Timshina D. K., Thappa D. M., Agrawal A. A clinical study of dermatoses in diabetes to establish its markers //Indian journal of dermatology. – 2012. – Т. 57. – №.1. – P. 20-25.

Caleb Harrison, BS; Vaishnavi Peyyety; Adriana Rodriguez Gonzalez, MD; Rutha Chivate, BS; Xu Qin, PhD; Margaret F. Zupa, MD, MS; Maya I. Ragavan, MD, MPH, MS; Mary Ellen Vajravelu, MD, Original Investigation | Diabetes and Endocrinology Prediabetes Prevalence by Adverse Social Determinants of Health in Adolescents MSHPJAMA Network Open. 2024;7(6):e2416088. doi:10.1001/jamanetworkopen.2024.16088 June 11, 2024 1/11.

Ponti G., Luppi G., Losi L., Giannetti A., Seidenari S. Leser-Trelat syndrome in patients affected by six multiple metachronous primitive cancers. J Hematology Oncol 2010 Jan 11; 3: 2.

Pociot F., Lernmark Å. Genetic risk factors for type 1 diabetes //The Lancet. – 2016. – Т. 387. – №. 10035. – P. 2331-2339.

Reaven G.M. The role of insulin resistance in the pathogenesis and treatment of non insulin dependent diabetes mellitus. Am J Med 1983; 74:

Wali V., Wali V. V. Assessment of various biochemical parameters and BMI in patients with skin tags //Journal of clinical and diagnostic research: JCDR. – 2016. – Т. 10. – №.1. – P. BC09.

Wieland C.N., Kumar N. Sign of Leser-Trelat. Int J Dermatol. 2008 Jun; 47 (6): 643—4.

Wolff К., Goldsmith L., Katz S.I., Gilchrest B.A., Paller A.S., Leffell D.J., eds. Fitzpatrick s Dermatology in General Medicine, 7th ed. New York: McGraw-Hill Medical; 2008. vol. : Fitzpatrick's Dermatology in General Medicine, seventh edition, McGraw-Hill Medical 2013: P.1635—36.

Rizaev JA, Khazratov AI, Iordanishvili AK Morphofunctional characteristics of the mucous membrane of the masticatory apparatus in experimental carcinogenesis //Russian Journal of Dentistry. – 2021. – T. 25. – No. 3. – pp. 225-231.

Статья поступила в редакцию 21.07.2024; одобрена после рецензирования 21.08.2024; принята к публикации 24.08.2024.

The article was submitted 21.07.2024; approved after reviewing 21.08.2024; accepted for publication 24.08.2024.

Информация об авторах:

Хамидова Фарида Муиновна - д.м.н., доцент. Самаркандский государственный медицинский университет, Самарканд, Узбекистан. Е-mail: xamidova.m.05@mail.ru, https://orcid.org/0000-0001-6084-7025

Нуруллаев Джавохир Аскар оглы.- Термезский филиал Ташкентской медицинской академии, Термез, Узбекистан. Е-mail: nurillaevjavoxir65@gmail.com. https://orcid.org/ 0009-0005-9589-0513

Information about the authors:

Khamidova Farida Muinovna - candidate of medical sciences, associate professor. Samarkand State Medical University, Samarkand, Uzbekistan. E-mail: xamidova.m.05@mail.ru, https://orcid.org/0000-0001-6084-7025

Nurullayev Javohir Asqar o’gli - Termez branch of the Tashkent Medical Academy, Termez, Uzbekistan. Е-mail: nurillaevjavoxir65@gmail.com. https://orcid.org/ 0009-0005-9589-0513

Источники финансирования: Работа не имела специального финансирования.

Конфликт интересов: Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.

Вклад авторов:

Хамидова Ф.М. — идеологическая концепция работы,написание текста; редактирование статьи;

Нуруллаев ДЖ.А..- сбор и анализ источников литературы, написание текста.

Sources of funding: The work did not receive any specific funding.

Conflict of interest: The authors declare no explicit or potential conflicts of interest associated with the publication of this article.

Contribution of the authors:

Khamidova F.M.— ideological concept of the work, writing the text; editing the article;

Nurullayev J.А. - collection and analysis of literature sources, writing the text.

Published

2024-11-05