АРАКТЕРИСТИКИ, СТРУКТУРА И ФУНКЦИОНАЛЬНЫЕ ОСОБЕННОСТИ РЕЦЕПТОРОВ ОКСИТОЦИНА
Ключевые слова:
окситоцин, мутация гена рецептора окситоцина, сократительная функция маткиАннотация
В данном обзоре рассмотрены данные об эпигенетических изменениях гена окситоцина и гена рецептора окситоцина, выявлена связь с репродукцией у людей, и потенциальные последствия любых изменений и мутаций в гене, для матери и ребенка в краткосрочной и долгосрочной перспективе. Доказано, что метилирование гена рецептора окситоцина может оказывать влияние на ход родового процесса. Имеются убедительные доказательства влияния окситоцина на социальное поведение и антистрессовые эффекты как у матери, так и у новорожденного. Но все же, остается неизученным до конца эффект влияния изменений в гене рецептора окситоцина и его экспрессии на сократительную функцию миометрия.
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