DYNAMIC CHANGES IN THE LEVELS OF IL-6, IL-10 AND TNF-α CYTOKINES IN HELMINTHIASES AND THEIR DIAGNOSTIC AND PROGNOSTIC SIGNIFICANCE
Keywords:
helminthiasis, ascariasis, enterobiasis, hymenolepiasis, cytokines, IL-6, IL-10, TNF-α, inflammatory mediators, immune response, allergic diseases, biomarker, dewormingAbstract
This article analyzes the dynamic changes in the levels of IL-6, IL-10, and TNF-α cytokines in patients with intestinal helminthiases, particularly ascariasis, enterobiasis, and hymenolepiasis. The study highlights the activation of the immune response during helminth infections, the disruption of the balance between pro-inflammatory and anti-inflammatory mediators, and the relationship of these processes with the clinical course of the disease. The article substantiates that the determination of IL-6, IL-10, and TNF-α cytokines may serve as an important diagnostic and prognostic criterion for assessing the activity and severity of helminthiases, the risk of allergic complications, and treatment effectiveness.
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