ASSESSMENT OF COGNITIVE FUNCTIONS IN PATIENTS WITH MULTIPLE SCLEROSIS

Authors

  • Oripov Shokhrukhbek Kaxramon ugli
  • Madjidova Yokuthon Nabievna

Keywords:

multiple sclerosis, cognitive impairment, neuropsychological assessment, MMSE, MoCA, SDMT, PASAT

Abstract

The article presents an assessment of cognitive functions in patients with multiple sclerosis. A total of 30 patients aged 20 to 45 years with varying disease duration and severity were examined. Neuropsychological assessment included the following scales: MMSE, MoCA, SDMT, and PASAT. Cognitive impairment was detected in the majority of patients (70%) and was mainly characterized by decreased information processing speed, impaired attention, memory deficits, and executive dysfunction. It was demonstrated that the MoCA scale, as well as SDMT and PASAT tests, are more sensitive compared to MMSE in detecting early cognitive impairment. A significant correlation was found between the severity of cognitive deficit and the level of disability according to the EDSS scale. The obtained results highlight the importance of early diagnosis and comprehensive assessment of cognitive functions in patients with multiple sclerosis in order to ensure timely correction and improve quality of life.

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Published

2026-05-15