RISK FACTORS FOR DEVELOPMENT OF VASCULAR DEMENTIA
Keywords:
vascular dementia, moderate cognitive impairmentAbstract
Vascular dementia is an important medical and social problem. In order to study the role of risk factors in the development of vascular dementia, a clinical neuroimaging study was carried out in 45 patients with vascular dementia aged 55 to 80 years. The control group consisted of 31 patients with moderate cognitive impairment (MCI) associated with stage II discirculatory encephalopathy. Prognostically significant risk factors for the development of vascular dementia in patients aged 50-59 years were coronary artery disease and hyperlipidemia, at the age of 60-69 years - coronary artery disease and diabetes mellitus, at the age of 70-79 years - hyperlipidemia. A neuroimaging study showed an association between the development of dementia in patients with MCI and the localization and prevalence of diffuse changes in the white matter of the brain.
References
Rakhimbaev G.S., Tolibov D.S. Prevalence and risk factors for the development of Alzheimer's type dementia. Vestn. TMA 2013; 3: 68-74.
Tolibov D.S. Neuropsychological features of Alzheimer's disease. Vestn. TMA 2013; 2: 72-76.
Алексеевич ГЮ, Родиков МВ, Можейко ЕЮ и др. Проблемы когнитивной дисфункции после аорто-коронарного шунтирования. Сибирское медицинское обозрение. 2015;(6):30-6.
Остроумова ОД, Черняева МС, Головина ОВ. Фибрилляция предсердий как фактор риска развития когнитивных нарушений и деменции. Возможности антикоагулянтной терапии в их профилактике. Кардиология. 2018;58(9):76-88.
Парфенов ВА, Старчина ЮА. Когнитивные расстройства и их лечение при артериальной гипертонии. Нервные болезни. 2015; (1):16-22.
Bhamidipati D, Goldhammer JE, Sperling MR, et al. Cognitive Outcomes After Coronary Artery Bypass Grafting. J Cardiothorac Vasc Anesth. 2017 Apr;31(2):707-718.
Fisher TJ, Schwartz AC, Greenspan HN, Heinrich TW. Dementia: A complex disease with multiple etiologies and multiple treatments. Int J Psychiatry Med. 2016;51(2):171-81.
Gorelick PB. Blood Pressure and the Prevention of Cognitive Impairment. JAMA Neurol. 2014 Oct;71(10):1211-3.
Kalantarian S, Stern TA, Mansour M, Ruskin JN. Cognitive impairment associated with atrial fibrillation: a meta-analysis. Ann Intern Med. 2013 Mar 5;158(5 Pt 1):338-46.
Kwok CS, Loke YK, Hale R, et al. Atrial fibrillation and incidence of dementia: a systematic review and meta-analysis. Neurology. 2011 Mar 8;76(10):914-22.
Mansur RB, Lee Y, Zhou AJ, et al. Determinants of cognitive function in individuals with type 2 diabetes mellitus: A meta-analysis. Ann Clin Psychiatry. 2018 Feb;30(1):38-50.
Umegaki H. Type 2 diabetes as a risk factor for cognitive impairment: current insights. Clin Interv Aging. 2014 Jun 28;9:1011-9.
Vincent C, Hall PA. Executive Function in Adults With Type 2 Diabetes: A Meta-Analytic Review. Psychosom Med. 2015 Jul-Aug;77(6): 631-42.
World Health Organization. Dementia: a public health priority. World Health Organization; 2013. 102 p. http://www.who.int/iris/han-dle/10665/112502.
