FEATURES OF IDENTIFICATION AND TREATMENT OF CEREBROASTENIC SYNDROME IN THE POSTOVIDE PERIOD

Authors

  • Shodiev Ulugbek Doniyor ugli
  • Rakhimbayeva Gulnara Sattarovna

Keywords:

SARS-CoV-2, COVID-19, coronavirus, virus life cycle, pathogenesis, cytokine storm, ACE2 receptor, adhesive protein, immune response, inflammation, interleukins, virus replication, cell invasion, respiratory distress syndrome

Abstract

The COVID-19 pandemic, caused by the SARS-CoV-2 virus (Severe Acute Respiratory Syndrome Coronavirus 2), has become one of the most significant challenges for global healthcare in the 21st century. Since its first detection in Wuhan, China, in December 2019, the pathogen has spread worldwide, affecting millions of people and causing a wide range of clinical manifestations - from asymptomatic forms to severe respiratory disorders with fatal outcomes. SARS-CoV-2 belongs to the Coronaviridae family of coronaviruses and is a membrane RNA virus with a positive polarity of the genome. Understanding the life cycle of the virus, the mechanisms of COVID-19 pathogenesis, and the characteristics of cytokine storm development are crucial for developing effective therapeutic strategies and preventive measures.

References

Алексеева Т.М., Балунов О.А., Станкевич П.Б. Неврологические осложнения COVID-19 // Неврология, нейропсихиатрия, психосоматика. – 2021. – Т. 13, № 2. – С. 14-24.

Белопасов В.В., Яшу Я.С., Самарцев И.Н. Постковидный синдром: клинические проявления, патогенез и подходы к лечению // Журнал неврологии и психиатрии им. С.С. Корсакова. – 2022. – Т. 122, № 3. – С. 7-15.

Войтенков В.Б., Скрипченко Н.В., Иванова Г.П. Церебро-астенический синдром у детей после COVID-19: диагностика и реабилитация // Педиатр. – 2021. – Т. 12, № 4. – С. 56-63.

Дамулин И.В., Екушева Е.В. COVID-19 и нервная система // Неврологический журнал. – 2020. – Т. 25, № 3. – С. 11-18.

Захаров В.В., Вознесенская Т.Г. Когнитивные нарушения после COVID-19 // Журнал неврологии и психиатрии им. С.С. Корсакова. – 2021. – Т. 121, № 11. – С. 5-12.

Котов С.В., Рудакова И.Г., Исакова Е.В. Астенический синдром в постковидном периоде: патогенез и терапевтические подходы

// Эффективная фармакотерапия. – 2021. – Т. 17, № 28. – С. 24-31.

Левин О.С., Васенина Е.Е., Ахметзянова Э.Х. Постковидный синдром с позиций невролога // Современная терапия в психиатрии и неврологии. – 2022. – № 1. – С. 4-14.

Путилина М.В. Церебро-астенический синдром при COVID-19: механизмы развития и возможности коррекции // РМЖ. Медицинское обозрение. – 2021. – Т. 5, № 8. – С. 456-461.

Khaydarova Dildora Kadirovna, Samadov Alibek Uktamovich. Current issues in the development of neuroprotective therapy in ischemic stroke. Web of Scientist: International Scientific Research Journal 2021. P. 6-10.

SH. I. Nasritdinova D. K. Xaydarova Peculiarities of the Neurological Status of Pregnant Women and Parents Infected with Covid-19 During Different Times of Gestation. Central asian journal of medical and natural sciences. Volume: 02. 2021. Р. 182-188.

Bai F., Tomasoni D., Falcinella C. et al. Female gender is associated with long COVID syndrome: a prospective cohort study // Clinical Microbiology and Infection. – 2022. – Vol. 28, № 4. – P. 611.e9-611.e16.

Published

2026-01-07