ОБСТРУКТИВНОЕ АПНОЭ СНА КАК МОДИФИЦИРУЕМЫЙ ФАКТОР РИСКА ЦЕРЕБРОВАСКУЛЯРНЫХ ЗАБОЛЕВАНИЙ: ИНТЕГРАТИВНЫЙ ПОДХОД К ИХ ПРОФИЛАКТИКЕ И ТЕРАПИИ
Ключевые слова:
обструктивное апноэ сна, нейродегенерация, когнитивные нарушения, инсульт, глимфатическая система, нейровоспаление, СИПАП-терапия, биомаркерыАннотация
Обструктивное апноэ сна (ОАС) является независимым фактором риска развития когнитивных нарушений. Согласно последним исследованиям (Andreu et al., Sleep Medicine Reviews, 2024) [1]., интермиттирующая гипоксемия при ОАС приводит к структурным изменениям головного мозга. Патогенетическая роль обструктивного апноэ сна (ОАС) в развитии неврологической патологии остается недостаточно подтвержденными в клинической практике.
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