GIYEN-BARRE SINDROMINING TURLI SHAKLLARIDA MONOTSITAR XEMOATTRAKTANT OQSIL-1 VA SISTATIN C NING PATOGENEZI VA DIAGNOSTIKADAGI ROLI
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Giyen-Barre sindromi, monotsitar xemoattraktant oqsil-1, sistatin S, demiyelinizatsiyalovchi polineyropatiya (OVDP), aksonal shakllar (OMSAN, OMAN), biomarkerlar##article.abstract##
Giyen-Barre sindromi (GBS) – bu periferik nervlarning demiyelinizatsiyasi va aksonal shikastlanishi bilan tavsiflanadigan o'tkir yallig'lanishli polineyropatiya. Tadqiqotda GBS ning turli klinik shakllarida monotsitar xemoattraktant oqsil-1 (MXO-1) va sistatin S darajalari o‘rganildi. Natijalar shuni ko‘rsatdiki, o'tkir motor-sensor aksonal neyropatiya (OMSAN) bilan og‘rigan bemorlarda MXO-1 va sistatin S darajalari boshqa shakllarga nisbatan sezilarli darajada oshgan. Olingan ma’lumotlar ushbu biomarkerlarnng GBS patogenezidagi roli va ularning potensial diagnostik ahamiyatiga ishora qiladi.
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